Vertigo
Vertigo - an illusion of motion where no motion exists (not to be confused with syncope/pre-syncope)
Seek details of - onset/ duration/repetition/hearing/tinnitus/headache/vomiting/ double vision/ recent medication
Differentiate between central and peripheral vertigo, since the former are almost always a result of serious pathology
Clinical signs
Central
- Less intense
- Not positional
- Hearing rarely affected
- Nystagmus not inhibited by ocular fixation
- Brain stem /cerebellar signs
Hallpike (with central)
- No latency of nystagmus
- Nystagmus non-fatiguing
- Multidirectional
- Vertigo lasts >1min
Peripheral
- Intense spinning / swaying
- Aggravated by position
- Altered hearing / tinnitus
- Nystagmus inhibited by ocular fixation
Hallpike (with peripheral)
- 2-20s latency
- fatigue with repeat testing
- unidirectional
- <1min

*patient sitting on trolley, rapidly lowered to supine position with physician controlling head. Head rotated 45 degrees left then right
| Pattern Types | Nystagmus Characteristics | Typical causes |
|---|---|---|
Peripheral patterns * |
Burst of upbeat-torsional nystagmus, lasting < 30 seconds, triggered by the Dix-Hallpike test to one side. Unidirectional spontaneous (i.e., primary gaze) nystagmus, with ↑ in velocity in the direction of the nystagmus fast phase and ↓ velocity in the opposite direction. E.g. left beating nystagmus in primary gaze, with an increase in velocity with left gaze, and a decrease (but not reversal) with right gaze. |
BPPV
Vestibular neuronitis (labyrinthitis) |
Central Patterns |
Spontaneous vertical nystagmus (upbeat or downbeat). Gaze-evoked direction changing nystagmus (i.e., persistent left beating on left gaze and then persistent right beating on right gaze). Persistent downbeating nystagmus triggered by a positional test such as the Dix-Hallpike test. § |
Stroke, multiple sclerosis Chiari malformation Meds (e.g., antiepileptics) stroke, multiple sclerosis, cerebellar degenerative disorder |
Physiological patterns | Persistent downbeating nystagmus triggered by a positional test such as the Dix-Hallpike test. |
|
BPPV = benign paroxysmal positional vertigo. *For peripheral vestibular nystagmus, the velocity of nystagmus typically increases by inhibiting visual fixation and decreases by encouraging visual fixation. However, the effect of visual fixation does not discriminate one peripheral vestibular disorder from another. § The Dix-Hallpike test is a specific positional test to asses for positional nystagmus. The patient sits upright and the head is turned about 450 to one side. The patient is then quickly guided by the physician down to a supine position with the head extended over the end of the examining table. In this position, the eyes are observed for nystagmus triggered by the test. The patient is then brought back to the sitting position and the test is then repeated with the head turned to the opposite side. | ||
Causes
Causes of central vertigo
- Cerebellar - CVA infarct/bleed **
- Brainstem
- CVA eg lateral medullary syndrome
- other infarcts of caudal pons
- neoplasm
- MS
- Trauma
- Check signs base of skull fracture
Unilateral sensorineural loss needs tumour exclusion (ENT opd). The whisper test with finger-rub distraction should be followed up with Rinne's and Weber's to establish basis of hearing deficit.
NOTE - cerebellar haemorrhage suggested by acute ataxia and vertigo +/- headache +/- nausea and vomiting with no paralysis is a neurosurgical emergency and requires urgent CT and neuosurgical opinion
Causes of peripheral vertigo
- Meniere's (triad)
- Bouts of vertigo, tinnitus & progressive deafness
- Vestibular neuronitis
- no hearing loss
- Benign Positional vertigo
- particularly provoked by altered position
- Drugs
- aspirin affects the cochlea giving rise to tinnitus
- aminoglycosides affect vestibular apparatus primarily
- Suppurative labyrinthitis - from recurrent otitis media / mastoiditis etc.
- Acoustic schwannoma and meningioma
- gradual onset, pre-ceded by hearing loss
Treatment
Peripheral features positive
- Stop triggering drugs if appropriate
- Chronic hearing loss - discuss with ENT
- ? Benign positional vertigo - try repositioning manoeuvre Cochrane
- Other - brief course stemetil & GP review
Central features positive
- Treatment as per cause
- Urgent CT if ? cerebellar lesion / base skull #
- Neurology review if ? MS
- Refer medics if ? CVA
Drug treatment
Check eBNF (left margin), Stemetil 5mg tds, Antihistamines (eg cyclizine PO tds)


